SUNGKYUNKWAN UNIVERSITY SCHOOL OF MEDICINE

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Graduate Programs

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    Uncontrolled, uncoordinated and unexpectable cell growth is what we called, tumor.
    This is due to the broken immune system which becomes friend of tumor. In order to find the way to impede tumor proliferation, knowledge of the basic mechanisms of the immune system must be increased rapidly. We are updating how tumor cells compromise and reprogram the immune system by development and learning.We are focusing on developing model systems to investigate immune cells status during the development of tumor, to figure out anti-cance r targets and to control tumorigenesis by E3 ubiquitin ligase and phosphatase. This research includes skilled experimental technology and competent students to study the function of specific immune cells in tumor microenvironment. Using improved cutting-edge methodologies such as establishing tumor microenvironment, sorting immune cells by multiplex fluorescence and treating adenovirus vaccines underlies how tumor and immune cell's communication influence signaling molecules and pathway. These advances in understanding the role of immune system in tumor are able to cope with the most pressing disease of the present age, exploiting perception into their underlying mechanisms and uncovering novel immunotherapy strategies.

    Course Work

    Course Work: Core Subjects (Common)
    Core Subjects (Common)
    Human Physiology
    Current Topics in Cell Biology
    Biomedical Big Data Science
    Introduction to Basic Medical Science
    Course Work: Core Subjects (Program)
    Core Subjects (Program)
    Tumor Biology
    Cancer Metabolism
     
     
    Course Work: Elective Subjects (Program)
    Elective Subjects (Program)
    Tumor Microenvironment
    Cancer Stem Cell Biology
    Cancer Immunology
     
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    According to the Precision Medicine Initiative, precision medicine is
    "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person." The research goal of Precision Medicine Unit is to integrate clinical data with genomic, environmental, and microbiome data from patients so that we can understand diseases better and develop better prevention methods with more precise therapies.

    Course Work

    Course Work: Core Subjects (Common)
    Core Subjects (Common)
    Human Physiology
    Current Topics in Cell Biology
    Biomedical Big Data Science
    Introduction to Basic Medical Science
     
    Course Work: Core Subjects (Program)
    Core Subjects (Program)
    Environmental Epidemiology
    Precision Medicine and Targeted Therapy
    Gut Microbiota and Metabolic Diseases
     
     
    Course Work: Elective Subjects (Program)
    Elective Subjects (Program)
    Computational Biology
    Spatiotemporal Analysis Ssing Health
    and Environmental Big Data 1,2
    Introduction to Therapeutic Sciences
    Introduction to Future Biomedical Sciences

    * Research Subjects: Master’s thesis research 1, 2;
    Doctoral thesis research 1, 2, 3, 4

  • Research in the Development and Regenerative Medicine Unit aims to answer key ques tions in developmental biology, stem cell/niche interactions, and organ regeneration.
    In consideration of the enormous promise of regenerative medicine in the development of therapeutic strategies for human diseases, understanding molecular mechanisms underlying cell fate control during organ development and organ repair processes has great potential. Another goal of this unit is to bridge basic research with disease modeling and perform translational investigations to elucidate mechanisms of human disease. The Development and Regenerative medicine Unit aims to provide multidisciplinary training within the graduate program of SKKUSOM.

    Course Work

    Course Work: Core Subjects (Common)
    Core Subjects (Common)
    Human Physiology
    Current Topics in Cell Biology
    Biomedical Big Data Science
    Introduction to Basic Medical Science
    Course Work: Core Subjects (Program)
    Core Subjects (Program)
    Developmental Biology
    Cancer Stem Cell Biology
     
     
    Course Work: Elective Subjects (Program)
    Elective Subjects (Program)
    Molecular and Cell Biology
    of Human Disease
    Gut Microbiota and Metabolic Diseases
     
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    Although the modern society has a lot of drugs and tools for treating infectious diseases, infection is still a big threat for human beings.
    To combat many infectious agents including newly emerging agents, we need to understand molecular mechanisms of their pathogenesis and the host’s immune system. Infection-immunity research groups at SKKU-SOM use advanced molecular biology, experimental animals, and clinical big data analysis to study interactions between microbes and hosts. Our groups include bacteriologists, virologists, parasitologists, immunologists, and clinical infection scientists.

    The immune system is also important for the control of cancers. Cancer immunology is a hot field to provide modalities for cancer treatment. In cancer patients, the immune system that should recognize cancer cells becomes unable to kill cancer cells. This phenomenon of immune exhaustion in the cancer microenvironment is due to complex interactions among cancer cells, cancer stromal cells, and immune cells. To overcome this phenomenon for treating cancer patients, we are studying cancer-fighting immune cells including T and B lymphocytes and their cellular characteristics.

    Another important disease in this field is autoimmune disease that is increasing in advanced countries. The complex immune system sometimes fails to control their own activity and eventually triggers damage to own tissues and inflammation. Our immune system contains components to inhibit overactivity of the immune system. We need to study this regulatory component of the immune system. Our group is also interested in autoimmune diseases using animal models and clinical patients.

    Course Work

    Course Work: Core Subjects (Common)
    Core Subjects (Common)
    Human Physiology
    Current Topics in Cell Biology
    Biomedical Big Data Science
    Introduction to Basic Medical Science
     
    Course Work: Core Subjects (Program)
    Core Subjects (Program)
    Molecular and Cellular Immunology
    Current Topics of Infection
    and Inflammation
     
     
    Course Work: Elective Subjects (Program)
    Elective Subjects (Program)
    Cancer Immunology
    Molecular Genetics of Bacteria
    Infectious Disease Epidemiology
    Advanced Medical Nicrobiology
    Advanced Molecular Virology
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    A major focus of our unit's research lies in understanding how deregulations in metabolism and genetic backgrounds contribute to metabolic diseases and aging.
    Our faculty members in this program use wet and dry lab techniques from cells to organisms to identify and understand underlying molecular mechanisms and cellular pathways involved in metabolism, human genetic diseases, and aging. Model systems including genetically altered mice and in vitro cell and organoid culture systems are used as main tools of this program. Ongoing efforts include research on adipose and muscle biology, aging, cancer metabolism, cardiovascular biology, diabetes, obesity, exercise metabolism, microbiota, immunometabolism, mitochondria, and stem cells. The unit is keen to contribute to the translation of fundamental discoveries into clinical advances to treat metabolic disorders and genetic diseases.

    Course Work

    Course Work: Core Subjects (Common)
    Core Subjects (Common)
    Human Physiology
    Current Topics in Cell Biology
    Biomedical Big Data Science
    Introduction to Basic Medical Science
    Course Work: Core Subjects (Program)
    Core Subjects (Program)
    Biochemistry of Metabolism
    Understanding the Molecular
    Basis of Rare Diseases
     
    Course Work: Elective Subjects (Program)
    Elective Subjects (Program)
    Molecular and Cell Biology
    of Human Disease
    Gut Microbiota and Metabolic Diseases
     
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    Understanding how the nervous systems are organized, how they develop, and how they function to generate behavior are fundamental questions in Neuroscience.
    These questions can be explored to identify the fundamental principles and mechanisms that govern the assembly and function of neurons and neural circuits with environmental communication within nervous system. Largely boosted by rapid technical advances, neuroscience is nowadays progressing at an impressive pace.

    The Neuroscience research groups at the SKKU-SOM use cutting-edge technology and computational approaches to study the formation and function of neural circuits in different model systems including the fruit fly, mouse as well as human.

    The major challenge facing our research groups is to determine the morphogenesis of axons and dendrites and formation and refinement of synapses, which is key steps in the establishment of neural circuits in the brain, to regenerate and reconstruct neural activity after injury, and to understand of how the nervous system functions both in healthy brain and how these mechanisms are deregulated in neurological diseases including developmental, psychiatric and neurodegenerative disorders such as Alzheimer and Parkinson's. Ultimately, these studies will lay the foundation for the development of new therapeutic approaches in the treatment of various neurologic disorders.

    Course Work

    Course Work: Core Subjects (Common)
    Core Subjects (Common)
    Human Physiology
    Current Topics in Cell Biology
    Biomedical Big Data Science
    Introduction to Basic Medical Science
     
     
     
    Course Work: Core Subjects (Program)
    Core Subjects (Program)
    Neurophysiology
    Neuroscience
     
     
     
     
     
    Course Work: Elective Subjects (Program)
    Elective Subjects (Program)
    Neuro Signaling
    Neuropharmacology and
    Convergence Research Trends
    Calcium Signaling
    Brain Diseases:
    Neurodegenerative Diseases
    Advanced Neurohistology