SUNGKYUNKWAN UNIVERSITY SCHOOL OF MEDICINE
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Jee-Yin Ahn
Jee-Yin Ahn PhD
| Graduate Program | Neuroscience |
| Research Area | Brain Development/ Death and Recovery of nerve cells |
| Laboratory | Neural Development and Regeneration Laboratory |
| jeeahn@skku.edu | |
| Tel | +82-31-299-6134 |
Education & Careers
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1995-2000 B.S/M.S/Ph.D. Department of Genetic Engineering, Hallym University
2002-2004 Post-Doctoral Fellow, Emory University School of Medicine, USA.
2011-2012 Visiting Professor, University of California San Francisco (UCSF) School of Medicine.
2005-Present Assistant/Associate/Full Professor, Sungkyunkwan University School of Medicine
Research Interest
The goal of our research is to identify the fundamental mechanisms and principles that govern neuronal death and connectivity of neural circuits in the brain development and disease and to determine how these mechanisms are deregulated in neurological diseases. Currently our lab focused on the elucidation of 1) the regulation of neuron death in brain disease, 2) the intrinsic mechanisms regulating the neural development including growth cone formation and synapse function. We are also very interested in 3) neurodevelopment and regeneration control after CNS injury using mouse model.
Representative Research Achievements
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1. Ko et al.,(2019) The roles of multifunctional protein EBP1 from development to disease Proc Natl Acad Sci 116 (49) 24852-24860
2. Hwang et al.,(2020) Dysregulation of epigenetic control contributes to Schizophrenia-like behavior in Ebp1+/- mice Int J Mol Sci. 921(7):2609
3. Ko et al., (2018) Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling Stem cell research & Therapy 219(1):326
4. Jin et al., (2018) Akt mediates radixin phosphorylation and prevents proteasomal degradation, contributing F-actin binding and axon growth in hippocampal neuron Scientific Reports 8(1):2557
5. Ko et al., (2016) Akt1/Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration eLife 5:e20799