1. Translesion DNA synthesis (TLS) across carcinogen-modified DNA lesions by DNA polymerases.
2. The role of human DNA polymerases & their genomic variations in mutagenesis & carcinogenesis.
3. Identification and development of anticancer therapy resistance gene markers, genotoxicity indexes and in vitro screening systems.
4. Interrelations of three R (DNA replication, repair, recombination) processes against DNA damage and its disease association.