Our laboratory conducts basic and translational studies related to innate immunity and cancer immunotherapy.
We have made major contributions to our understanding of the crosstalk between innate immune signals and autophagy in cancer diseases.
Current studies focus on the molecular mechanism and pathogenesis of cancer diseases regulated by autophagy and innate cellular components, working toward the goal of identifying novel therapeutic targets and strategies for cancer immunotherapy.
Major Areas of Research
&9702 Crosstalk between innate immune signals and autophagy in cancer diseases
&9702 Basic properties of innate immune cells in tumor microenvironment (TME)
&9702 Functional roles of Toll-like receptors in tumor microenvironment (TME)
&9702 Development of Humanized PDX mice in cancers