The Ryu Lab is a multidisciplinary research group, exploring to find
(1) the cellular sensors or regulators answering to energy stress and aging,
(2) the retrograde signaling pathways relaying from a stressed organelle to nucleus (e.g. mitonuclear mitochondrial stress signaling),
(3) the gut-metabolic organ axis reshaping on our whole-body energy metabolism, and
(4) the biomolecules and drugs enhancing mitochondrial function and proteostasis. Our challenges will lead to identify and develop translational treatment strategies for metabolic and age-associated diseases.
Our lab prefers to practice a combinational approach of the wet-labs (traditional biochemical & molecular cell biology techniques) and the dry-labs (Bioinformatics).