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전임교수

  • 세균학
  • (전화) 031-299-6223 / (fax)
  • ksko@skku.edu

    주요경력

    • 1994 서울대학교 미생물학과, 이학사
      1996 서울대학교 미생물학과, 이학석사
      2000 서울대학교 생명과학부, 이학박사 (미생물학)
      2000 - 2003 서울대학교 의과대학 미생물학교실 / 암연구소 postdoc fellow
      2003 - 현재 아태감염연구재단 (ARFID) 연구실장
      2007 - 현재 성균관대학교 의과대학 분자세포생물학교실 조교수, 부교수, 교수 (SKKU-Fellowship)

    주요관심연구

    • 본 연구실의 가장 주된 연구 주제는 병원성 세균의 항생제 내성이다. 20세기 중반 이후 ‘기적의 약’이라 불리며 수많은 생명을 살려낸 항생제는 항생제 내성으로 말미암아 그 효과를 잃어가고 있다. 이러한 항생제 내성은 우리나라 뿐만 아니라 전세계적인 문제로 떠오르고 있다. 본 연구실은 이와 관련한 항생제 내성의 메카니즘과 항생제 내성균의 출현 및 확산에 관한 연구를 수행하고 있다.

      (1) 병원성 세균의 항생제 내성 연구
      본 연구실은 주요 병원성 세균 (Streptococcus pneumoniae, Staphylococcus aureus, Enterococcus faecium, Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli 등)의 주요 병원성 세균의 항생제 내성을 연구한다. 이를 위하여 내성률을 측정하고 내성 균주에서의 내성 메카니즘을 밝히고 있다.

      (2) 병원성 세균의 출현 및 확산, 진화에 대한 연구
      본 연구실은 PFGE, MLST 등의 분자생물학적 방법 및 Genome 수준의 연구 방법을 이용하여 병원성 세균의 개체군 구조 및 진화를 연구한다. 이러한 연구를 통하여 고병원성 또는 항생제 내성을 갖는 세균의 clone을 찾아내고 이의 전파에 대해서 밝혀내고 분자적 진화에 대해 연구하고 있다.


    대표연구업적

    • * 2011년 이후 논문

      [2018]
      Kim SJ, Kim YJ, Ko KS*. Genomic analysis of consecutive Acinetobacter baumannii strains from a single patient. Frontiers in Microbiology (Accepted)
      (Corresponding author)

      Ko KS*. Antibiotic-resistant clones in gram-negative pathogens: presence of global clones in Korea. Journal of Microbiology (Accepted)
      (1st and corresponding author)

      Kim SY, Ko KS*. Effects of prophage regions in a plasmid carrying a carbapenemase gene on survival against antibiotic stress. International Journal of Antimicrobial Agents (Accepted)
      (Corresponding author)

      Kim SY, Ko KS*. Diverse plasmids harbouring blaCTX-M-15 in Klebsiella pneumoniae ST11 isolates from several Asian countries. Microbial Drug Resistance (Accepted)
      (Corresponding author)

      Baek JY, Kim SH, Kang CI, Chung DR, Peck KR, Song JH, Ko KS*. Emergence of an extensively drug-resistant (XDR) Streptococcus pneumoniae serotype 15A by capsular switching. International Journal of Medical Microbiology 2018, 308(8):986-989.
      (Corresponding author)

      Hong YK, Ko KS*. Development of colistin dependence in non-baumannii Acinetobacter species. International Journal of Antimicrobial Agents 2018 52(5):742-743.
      (Corresponding author)

      Kim SJ, Ko KS*. Diverse genetic alterations responsible for post-exposure colistin resistance in populations of the same strain of Klebsiella pneumonia. International Journal of Antimicrobial Agents 2018 52(3):425-429.
      (Corresponding author)

      Lee H, Baek JY, Kim SY, Jo HJ, Kang KJ, Ko JH, Cho SY, Chung DR, Peck KR, Song JH, Ko KS*. Comparison of virulence between matt and mucoid colonies of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 isolated from a single patient. Journal of Microbiology 2018 56(9):665-672.
      (Corresponding author)

      Joo EJ†, Kim SJ†, Baek M, Choi Y, Seo J, Yeom JS, Ko KS*. Fecal carriage of antimicrobial-resistant Enterobacteriaceae in healthy Korean adults. Journal of Microbiology and Biotechnology 2018 28(7):1178-1184.
      (Corresponding author)

      Heo ST†, Kwon KT†, Yoo JR, Choi JY, Lee KH, Ko KS*. The first case of necrotizing fasciitis caused by Skermanella aerolata infection mimicking Vibrio sepsis. Annals of Laboratory Medicine 2018 38(6):604-606.
      (Corresponding author)

      Cha K, Oh HK, Jang JY, Jo Y, Kim WK, Ha GU, Ko KS, Myung H. Characterization of two novel bacteriophages infecting multidrug-resistant (MDR) Acinetobacter baumannii and evaluation of their therapeutic efficacy in vivo. Frontiers in Microbiology 2018 9:696.
      (Co-author)

      Hong YK, Lee JY, Ko KS*. Colistin resistance in Enterobacter spp. isolates in Korea. Journal of Microbiology 2018 56(6):435-440.
      (Corresponding author)

      Baek JY, Kang CI, Kim SH, Ko KS, Chung DR, Peck KR, Lee NY, Song JH. Emergence of multidrug-resistant clones in levofloxacin non-susceptible Streptococcus pneumoniae isolates in Korea. Diagnostic Microbiology and Infectious Disease 2018 91(3):287-290.
      (Coauthor)

      Lee JY, Lim SK, Choi Y, Moon DC, Shin J, Ko KS*. Whole sequences and characteristics of mcr-1-harboring plasmids of Escherichia coli strains isolated from livestock in South Korea. Microbial Drug Resistance 2018 24(4):289-492.
      (Corresponding author)

      Wi YM, Greenwood-Quaintance KE, Schuetz AN, Ko KS, Peck KR, Song JH, Patel R. Activity of Ceftolozane-Tazobactam against carbapenem-resistant, carbapenemase nonproducing Pseudomonas aeruginosa and associated resistance mechanisms. Antimicrobial Agents and Chemotherapy 2018 62(1):e01970-17.
      (Coauthor)


      [2017]
      Ko KS*, Choi Y, Lee JY. Old drug, new findings: colistin resistance and dependence of Acinetobacter baumannii. Precision and Future Medicine 2017 1(4):159-167.
      (First and Corresponding author)

      Kim J, Lee JY, Lee H, Choi JY, Kim DH, Wi YM, Peck KR, Ko KS*. Microbiological features and clinical impact of the type VI secretion system (T6SS) in Acinetobacter baumannii isolates causing bacteremia. Virulence 2017 8(7):1378-1389.
      (Corresponding author)

      Lee JY, Chung ES, Ko KS*. Transition of colistin dependence into colistin resistance in Acinetobacter baumannii. Scientific Reports 2017 7:14216.
      (Corresponding author)

      Shin J, Baek JY, Chung DR, Ko KS*. Instability of the IncFII-type plasmid carrying blaNDM-5 in a Klebsiella pneumoniae isolate. Journal of Microbiology and Biotechnology 201727(9):1711-1715.
      (Corresponding author)

      Baek JY*, Chung DR*, Ko KS*, Kim SH, Yang SJ, Kang CI, Peck KR, Song JH. Genetic alterations responsible for reduced susceptibility to vancomycin in community-associated methicillin-resistant Staphylococcus aureus strains of ST72. Journal of Antimicrobial Chemotherapy 2017 72(9):2454-2460.
      (Co-first author)

      Kim SY, Shin SY, Rhee JY, Ko KS*. Imipenem-resistant gram-negative bacterial isolates carried by persons upon medical examination in Korea. Journal of Microbiology 55(8):612-618, 2017.
      (Corresponding author)

      Chung ES, Lee JY, Rhee JY, Ko KS*. Colistin resistance in Pseudomonas aeruginosa that is not linked to arnB. Journal of Medical Microbiology 66(6):833-841, 2017
      (Corresponding author)

      Chung ES, Wi YM, Ko KS*. Variations in formation of persister cells against colistin in Acinetobacter baumannii isolates and its relationship with treatment failure. Journal of Antimicrobial Chemotherapy 72(7):2133-2135, 2017
      (Corresponding author)

      Wi YM, Choi JY, Lee JY, Kang CI, Chung DR, Peck KR, Song JH, Ko KS*. Antimicrobial effects of β-lactams on imipenem-resistant ceftazidime-susceptible Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 61(6):e00054-17, 2017.
      (Corresponding author)

      Wi YM, Choi JY, Lee JY, Kang CI, Chung DR, Peck KR, Song JH, Ko KS*. Emergence of colistin resistance in Pseudomonas aeruginosa ST235 clone in Korea. International Journal of Antimicrobial Agents 49(6):767-769.
      (Corresponding author)

      Ko KS*. The contribution of capsule polysaccharide genes to virulence of Klebsiella pneumoniae. Virulence 8(5):485-486, 2017.
      (Corresponding author)

      Cheong HS, Chung DR, Park M, Kim SH, Ko KS, Ha YE, Kang CI, Peck KR, Song JH. Emergence of an extended-spectrum β-lactamase-producing serotype K1 Klebsiella pneumoniae ST23 strain from Asian countries. Epidemiology & Infection 145(5):990-994, 2017.
      (Co-author)

      Park KS, Lee JH, Park M, Ko KS, Lee SH. How many mcr-1-harbouring bacteria were spreading geographically? Biomedical Research 28(4):1659-1663, 2017.
      (Coauthor)

      Park IH, Baek JY, Song JH, Ko KS*, Kim KH. Draft genome sequences of clinical isolates of serotype 6E Streptococcus pneumoniae from five Asian countries. Genome Announcements 5(10):e01728-16, 2017.
      (Co-corresponding author)

      Kim DH, Jung SI, Kwon KT, Ko KS*. The occurrence of diverse AbGRI1-type genomic islands in Acinetobacter baumannii global clone 2 (GC2) isolates from Korea. Antimicrobial Agents and Chemotherapy 61(2):e01972-16, 2017.
      (Corresponding author)

      Lee JY, Hong YK, Lee H, Ko KS*. High prevalence of non-clonal imipenem-nonsusceptible Enterobacter spp. isolates in Korea and their association with porin downregulation. Diagnostic Microbiology and Infectious Disease 87(1):53-59, 2017.
      (Corresponding author)

      Choi HJ, Kil MC, Choi JY, Kim SJ, Park KS, Kim YJ, Ko KS*. Characterization of successive Acinetobacter baumannii isolates from a deceased hemophagocytic lymphohistiocytosis patient. International Journal of Antimicrobial Agents 49(1):102-106, 2017
      (Corresponding author)

      [2016]
      Rhee JY, Song JH, Ko KS*. Current situation of antimicrobial resistance and genetic differences in Sternotrophomonas maltophilia complex. Infection and Chemotherapy 48(4):285-293, 2016.
      (Corresponding author)

      Rhee JY, Choi JY, Ko KS*. Efflux pump inhibitor carbonyl cyanide-m-chlorophenylhydrazone (CCCP) enhances bacteriostatic activity of trimethoprime-sulfamethoxazole against clinical Stenotrophomonas maltophilia isolates from Korea. Journal of Bacteriology and Virology 46(4):185-192, 2016.
      (Corresponding author)

      Choi MJ, Kim S, Ko KS*. Pathways regulating the pbgP operon and colistin resistance in Klebsiella pneumoniae strains. Journal of Microbiology and Biotechnology 26(9):1620-1628, 2016.
      (Corresponding author)

      Hong YK, Lee JY, Wi YM, Ko KS*. High rate of colistin dependence in Acinetobacter baumannii. Journal of Antimicrobial Chemotherapy 71(8):2346-2348, 2016.
      (Corresponding author)

      Joo EJ, Choi JY, Chung DR, Song JH, Ko KS*. Characteristics of the community-genotype sequence type 72 methicillin-resistant Staphylococcus aureus isolates that underlie their persistence in hospitals. Journal of Microbiology 54(6):451-458, 2016.
      (Corresponding author)

      Baek JY, Kang CI, Kim SH, Ko KS, Chung DR, Peck KR, Hsueh PR, Thamlikitkul v, So TM, Lee NY, Song JH, on behalf of the ANSORP Study Group. In vitro activity of Tedizolid phosphate against multidrug-resistant Streptococcus pneumoniae isolates from Asian countries. Diagnostic Microbiology and Infectious Disease 85(2):218-220, 2016.
      (Coauthor)

      Lee JY, Park YK, Chung ES, Na IY, Ko KS*. Evolved resistance to colistin and its loss due to genetic reversion in Pseudomonas aeruginosa. Scientific Reports 6:25543, 2016.
      (Corresponding author)

      Baek JY, Kim SH, Kang CI, Chung DR, Peck KR, Ko KS*, Song JH. Prevalence of antimicrobial resistant Streptococcus pneumoniae serotype 11A isolates in Korea, during 2004 -2013, due to the increase of multidrug-resistant clone, CC166. Infection, Genetics and Evolution 38:122-125, 2016.
      (Co-corresponding author)

      Shin J, Baek JY, Cho SY, Huh HJ, Lee NY, Song JH, Chung DR, Ko KS*. blaNDM-5-bearing IncFII-type plasmids of Klebsiella pneumoniae ST147 transmitted by cross-border transfer of a patient. Antimicrobial Agents and Chemotherapy 60(3):1932-1934, 2016.
      (Co-corresponding author)

      Kim SY, Rhee JY, Ko KS*. Complete sequences of blaKPC-2-harboring plasmid with a mosaic of IncN1- and IncN3-type plasmids in a Klebsiella pneumoniae isolate from South Korea. Antimicrobial Agents and Chemotherapy 60(2): 1167-1169, 2016.
      (Corresponding author)

      Kim JS, Cho DH, Park M, Chung WJ, Shin D, Ko KS, Kweon DH. CRISPR/Cas9-mediated re-sensitization of antibiotic-resistant Escherichia coli harboring extended spectrum β-lactamases. Journal of Microbiology and Biotechnology 26(2):394-401, 2016
      (Coauthor)

      Na IY, Chung ES, Jung CY, Kim DH, Shin J, Kang KJ, Kim ST, Ko KS*. Comparison of the virulence-associated phenotypes of five species of Acinetobacter baumannii complex. Journal of Microbiology and Biotechnology 26(1): 182-190, 2016.
      (Corresponding author)

      Lee JY, Choi MJ, Choi HJ, Ko KS*. Preservation of acquired colistin resistance in gram-negative bacteria. Antimicrobial Agents and Chemotherapy 60(1):609-612, 2016.
      (Corresponding author)


      [2015]
      Choi MJ, Ko KS*. Loss of hypermucoviscosity and increased fitness cost in colistin-resistant Klebsiella pneumoniae ST23 strains. Antimicrobial Agents and Chemotherapy 59(11):6763-6773, 2015.
      (Corresponding author)

      Wi YM, Park YK, Moon C, Ryu SY, Lee H, Ki HK, Cheong HS, Son JS, Lee JS, Kwon KT, Kim JM, Ha YE, Kang CI, Ko KS*, Chung DR, Peck KR, Song JH. The cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus blood isolates: their association with dysfunction accessory gene regulator (agr). Diagnostic Microbiology and Infectious Disease 83(3):286-291, 2015.
      (Co-Corresponding author)

      Shin J, Ko KS*. A plasmid bearing blaCTX-M-15 gene and phage P1-like sequences from ST11 Klebsiella pneumoniae isolate. Antimicrobial Agents and Chemotherapy 59(10):6608-6610, 2015.
      (Corresponding author)

      Kim DH, Ko KS*. AbaR-type genomic islands in non-Acinetobacter baumannii isolates from Korea. Antimicrobial Agents and Chemotherapy 59(9):5824-586, 2015. (September)
      (Corresponding author)

      Shin J, Ko KS*. Effect of plasmids harbouring blaCTX-M on the virulence and fitness of Escherichia coli ST131 isolates. International Journal of Antimicrobial Agents 46(2):214-218, 2015. (August)
      (Corresponding author)

      Park YK, Lee JY, Ko KS*. Transcriptomic analysis of colistin-susceptible and colistin-resistant isolates identifies genes associated with colistin resistance in Acinetobacter baumannii. Clinical Microbiology and Infection 21(8):765.e1-765.e7, 2015. (August)
      (Corresponding author)

      Heo ST, Yoo JR, Lee KH, Ko KS*. The First Case of Non-retrospective Clinical Identification of Severe Fever with Thrombocytopenia Syndrome Patient in 2013 in South Korea. Journal of Bacteriology and Virology 45(2):155-158, 2015.
      (Corresponding author)

      Kim DH, Ko KS*. A distinct alleles and genetic recombination of pmrCAB operon in species of Acinetobacter baumannii complex isolates. Diagnostic Microbiology and Infectious Disease 82:183-188, 2015.
      (Corresponding author)

      Shin J, Ko KS*. Reply to "Distribution of genotypes between CTX-M-producing and non-Extended-Spectrum-β-Lactamase-producing Klebsiella pneumoniae isolates". Antimicrobial Agents and Chemotherapy 59(7):4363, 2015.
      (Corresponding author)

      Na IY, Baek JY, Park IH, Kim DH, Song JH, Ko KS.* pspK gene prevalence and characterization of non-typeable Streptococcus pneumoniae isolates from Asian countries. Microbiology 161(5):973-979, 2015.
      (Corresponding author)

      Ko KS*, Choi JY, Kim J, Park MK. Citrobacter bitternis sp. nov. isolated from bitterns. Current Microbiology 70(6):894-897, 2015 (June).
      (First & Corresponding author)

      Kim DH, Ko KS*. ISAba15 ed into outer membrane protein gene carO in Acinetobacter baumannii. Journal of Bacteriology and Virology 45(1):51-53, 2015 (March)
      (Corresponding author)

      Sohn KM, Huh K, Baek JY, Kim YS, Kang CI, Peck KR, Lee NY, Song JH, Ko KS*, Chung DR. A new causative bacteria of infective endocarditis, Bergeyella cardium sp. nov. Diagnostic Microbiology and Infectious Disease 81(3):213-216, 2015 (March)
      (Co-corresponding author)

      Kim MS, Kim YD, Hong SS, Park K, Ko KS, Myung H. Phage encoded colanic acid-degrading enzyme permits lytic phage infection of a capsule-forming resistant mutant Escherichia coli strain. Applied and Environmental Microbiology 81(3):900-909, 2015 (February)
      (Co-author)

      Yoon JH, Yim HW, Ko KS*. A case of Paenibacillus pasadenensis bacteremia in a patient with acute respiratory distress syndrome after microsurgical clipping. Infection & Chemotherapy 47(1):64-67, 2015 (March)
      (Corresponding author)

      Choi MJ, Peck KR, Ko KS*. Mutant prevention concentration of tigecycline in Acinetobacter baumannii and Klebsiella pneumoniae clinical isolates. Journal of Antimicrobial Chemotherapy 70(2):621-622, 2015 (February)
      (Corresponding author)

      Park YK, Ko KS*. Effect of carbonyl cyanide 3-chlrophenylhydrazone (CCCP) on killing Acinetobacter baumannii by colistin. Journal of Microbiology 53(1):53-59, 2015 (January)
      (Corressponding author)

      [2014]
      Jeon JH, Hong MK, Lee JH, Lee JJ, Park KS, Karim AM, Jo JY, Kim JH, Ko KS, Kang LW, Lee SH. Structure of ADC-68, a novel carbapenem-hydrolyzing class C extended-spectrum β-lactamase, isolated from Acinetobacter baumannii. Acta Crystallographica Section D 70(11):2924-2936, 2014 (November)
      (Co-author)

      Baek JY, Park IH, So TM, Lalitha MK, Shimono N, Yasin RM, Carlos CC, Perera J, Thamlikitkul V, Hsueh PR, Van PH, Shibl AM, Song JH, Ko KS*. Prevalence and characteristics of Streptococcus pneumoniae “putative serotype 6E” isolates from Asian countries. Diagnostic Microbiology and Infectious Disease 80(4):334-337, 2014 (December)
      (Corresponding author)

      Choi MJ, Peck KR, Ko KS*. Mutant prevention concentrations of colistin when used in combination with other antimicrobial agents against Acinetobacter baumannii, Klebsiella pneumoniae and Pseudomonas aeruginosa clinical isolates. International Journal of Antimicrobial Agents 44(5):475-476, 2014 (November)
      (Corresponding author)

      Lee JY, Chung ES, Na IY, Kim H, Shin D, Ko KS*. Development of colistin resistance in pmrA, phoP, parR, and cprR-inactivated mutants of Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 69(11):2966-2971, 2014 (November)
      (Corresponding author)

      Choi JY, Ko EA, Kwan KT, Lee S, Kang CI, Chung DR, Peck KR, Song JH, Ko KS*. Acinetobacter sp. isolates from emergency departments in two hospitals of South Korea. Journal of Medical Microbiology 63(10): 1363-1368, 2014 (October)
      (Corresponding author)

      Croucher NJ, Hanage WP, Harris SR, McGee L, van der Linden M, de Lencastre H, Sá-Leão R, Song JH, Ko KS, Beall B, Klugman KP, Parkhill J, Tomasz A, Kristinsson KG, Bentley SD. Variable recombination dynamics during the emergence, transmission and ‘disarming’ of a multidrug-resistant pneumococcal clone. BMC Biology 12:49
      (Co-author)

      Croucher NJ, Chewapreecha C, Hanage WP, Harris SR, McGee L, van der Linden M, Song JH, Ko KS, de Lencastre H, Turner C, Yang F, Sá-Leão R, Beall B, Klugman KP, Parkhill J, Turner P, Bentley SD. Evidence for soft ive sweeps in the evolution of pneumococcal multidrug-resistance and vaccine escape. Genome Biology and Evolution 6(7):1589-1602, 2014.
      (Co-author)

      Kim SY, Choi HJ, Ko KS*. Differential expression of two-component systems, pmrAB and phoPQ, with different growth phases of Klebsiella pneumoniae in the presence or absence of colistin. Current Microbiology 69:37-41, 2014 (July)
      (Corresponding author)

      Wi YM, Kim SW, Chang HH, Jung SI, Kim YS, Cheong HS, Ki HK, Son JS, Kwon KT, Heo ST, Yeom JS, Ko KS, Kang CI, Chung DR, Peck KR, Song JH. Predictors of uropathogens other than Escherichia coli in patients with community-onset acute pyelonephritis. International Journal of Clinical Practice 68(6): 748-755, 2014 (June)
      (Coauthor)

      Baek JY, Park IH, Song JH, Ko KS*. Prevalence of Streptococcus pneumoniae ‘putative serotype 6E’ isolates in South Korea. Journal of Clinical Microbiology 52(6):2096-2099, 2014 (June)
      (Corresponding author)

      Kim J, Kang CI, Baek JY, Cho SY, Kim SH, Ko KS, Chung DR, Peck KR, Song JH. Treatment failure due to induction of ciprofloxacin resistance during combination therapy with colistin and ciprofloxacin in multidrug-resistant Pseudomonas aeruginosa bacteremia. International Journal of Antimicrobial Agents 43(4):391-393, 2014 (April)
      (Coauthor)

      Lee JY, Na IY, Park YK, Ko KS*. Genomic variations between colistin-susceptible and -resistant Pseudomonas aeruginosa clinical isolates and their effects on colistin resistance. Journal of Antimicrobial Chemotherapy 69(4):1248-1256, 2014 (May)
      (Corresponding author)

      Shin J, Ko KS*. Comparative study on genotype and virulence of CTX-M-producing and non-ESBL-producing Klebsiella pneumoniae isolates. Antimicrobial Agents and Chemotherapy 58(4):2463-2467, 2014 (April)
      (Corresponding author)

      Shin J, Ko KS*. Single origin of three plasmids bearing blaCTX-M-15 from different Klebsiella pneumoniae clones. Journal of Antimicrobial Chemotherapy 69(4):969-972, 2014 (April)
      (Corresponding author)

      Choi MJ, Lim SK, Jung SC, Ko KS*. Comparisons of CTX-M-producing Escherichia coli isolates from humans and animals in South Korea. Journal of Bacteriology and Virology 44(1):44-51, 2014 (March)
      (Corresponding author)

      Lee JY, Ko KS*. Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates. Diagnostic Microbiology and Infectious Disease 78(3):271-276, 2014 (March)
      (Corresponding author)

      Kim SY, Rhee JY, Shin SY, Ko KS*. Characteristics of community-onset NDM-1-producing Klebsiella pneumoniae isolates in Korea. Journal of Medical Microbiology 63(1):86-89, 2014 (January)
      (Corresponding author)

      Choi MJ, Ko KS*. Mutant prevention concentration of colistin in Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae clinical isolates. Journal of Antimicrobial Chemotherapy 69(1):275-277, 2014 (January)
      (Corresponding author)

      [2013]
      Choi JY, Ko G, Jheong W, Huys G, Seifert H, Dijkshoorn, Ko KS*. Acinetobacter kookii sp. nov., isolated from soil. International Journal of Systematic and Evolutionary Microbiology 63(12):4402-4406, 2013 (December)
      (Corresponding author)

      Kim DH, Choi JY, Kim HW, Kim SH, Chung DR, Peck KR, Thamlikitkul V, So TM, Yasin RMD, Hsueh PR, Carlos CC, Hus CC, Hsu LY, Buntaran L, Lalitha MK, Song JH, Ko KS*. Spread of carbapenem-resistant Acinetobacter baumannii global clone 2 in Asia and AbaR-type resistance islands. Antimicrobial Agents and Chemotherapy 57(11):5239-5246, 2013 (October).
      (Corresponding author)

      Ko KS*, Baek JY, Song JH. Capsular gene sequences and genotypes of ‘serotype 6E’ Streptococcus pneumoniae isolates. Journal of Clinical Microbiology 51(10):3395-3399, 2013 (October)
      (First and corresponding author)

      Kang CI, Cha MK, Kim SH, Ko KS, Wi YM, Chung DR, Peck KR, Lee NY, Song JH. Clinical and molecular epidemiology of community-onset bacteremia caused by extended-spectrum β-lactamase-producing Escherichia coli over a 6-year period. Journal of Korean Medical Science 28(7):998-1004, 2013 (July)
      (Coauthor)

      Kim SY, Shin J, Shin SY, Ko KS*. Characteristics of carbapenem-resistant Enterobacteriaceae isolates from Korea. Diagnostic Microbiology and Infectious Disease 76(4):486-490, 2013 (August).
      (Corresponding author)

      Park KH, Shin JH, Lee SY, Kim SH, Jang MO, Kang SJ, Jung SI, Chung EK, Ko KS, Jang HC. The clinical characteristics, carbapenem resistance, and outcome of Acinetobacter bacteremia according to genospecies. PLoS ONE 8(6): e65026, 2013 (June)
      (Coauthor)

      Kang CI, Wi YM, Ko KS, Chung DR, Peck KR, Lee NY, Song JH. Outcomes and risk factors for mortality in community-onset bacteremia caused by extended-spectrum-β-lactamase-producing Escherichia coli, with a special emphasis on antimicrobial therapy. Scandinavian Journal of Infectious Diseases 45(70):519-525, 2013 (July).
      (Coauthor)

      Lee JY, Peck KR, Ko KS*. ive advantages of two major clones of carbapenem-resistant Pseudomonas aeruginosa isolates (CC235 and CC641) from Korea: antimicrobial resistance, virulence, and biofilm-forming activity. Journal of Medical Microbiology 62(6):1015-1024, 2013 (June)
      (Corresponding author)

      Rhee JY, Choi JY, Choi MJ, Song JH, Peck KR, Ko KS*. Distinct groups and antimicrobial resistance of clinical Stenotrophomonas maltophilia complex isolates from Korea. Journal of Medical Microbiology 62(5):748-753, 2013 (May)
      (Corresponding author)

      Cheong HS, Ko KS, Kang CI, Chung DR, Peck KR, Song JH. Clinical significance of infections caused by plasmid-mediated AmpC β-lactamases and extended-spectrum β-lactamase-producing Escherichia coli. Infection 41(1):709-712, 2013 (February)
      (Coauthor)


      [2012]
      Shin SY, Choi JY, Ko KS*. Four cases of possible human infections with Delftia lacustris. Infection 40(6):709-712, 2012 (December)
      (Corresponding author)

      Ito T, Hiramatsu K, Tomasz A, de Lencastre H, Perreten V, Holden MTG, Coleman DC, Goering R, Giffard PM, Skov RL, Zhang K, Westh H, O''''Brien F, Tenover FC, Oliveira DC, Boyle-Vavra S, Laurent F, Kearns AM, Kreiswirth B, Ko KS, Grundmann H, Sollid JE, John, Jr JF, Daum R, Soderquist B, Buist G behalf of the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC). Guidelines for reporting novl mecA gene homologues. Antimicrobial Agents and Chemotherapy 56(10): 4997-4999, 2012 (October)
      (Coauthor)

      Choi JY, Kim Y, Ko EA, Park YK, Jheong W, Ko G, Ko KS*. Acinetobacter species isolates from a range of environments: species survey and observations of antimicrobial resistance. Diagnostic Microbiology and Infectious Disease 74:177-180, 2012 (October)
      (Corresponding author)

      Park CG, Kim BJ, Kim HY, Yun YJ, Ko KS, Miyamoto H, Kim BJ, Kook YH. Analysis of population structure among Korean and Japanese Legionella pneumophila isolates using hsp60 sequences. Microbiology and Immunology 56(8):572-578, 2012 (August)
      (Coauthor)

      Chung DR, Baek JY, Kim HA, Lim MH, Kim SH, Ko KS, Kang CI, Peck KR, Lee NY, Song JH. First report of vancomycin intermediate resistance in sequence type 72 community-genotype methicillin-resistant Staphylococcus aureus. Journal of Clinical Microbiology 18(4):446-452, 2012 (August)
      (Coauthor)

      Kim DH, Choi JY, Jung SI, Thamlikikul V, Song JH, Ko KS*. AbaR4-type resistance island including the blaOXA-23 gene in Acinetobacter nosocomialis isolates. Antimicrobial Agents and Chemotherapy 56(8):4548-4549, 2012 (August)
      (Corresponding author)

      Kim DH, Park YK, Ko KS*. Variations of AbaR4-type resistance island in Acinetobacter baumannii isolates from South Korea. Antimicrobial Agents and Chemotherapy 56(8):4544-4547, 2012 (August)
      (Corresponding author)

      Wi YM, Kim JM, Joo EJ, Ha YE, Kang CI, Ko KS, Chung DR, Song JH, Peck KR. High vancomycin minimum inhibitory concentration is a predictor of mortality in meticillin-resistant Staphylococcus aureus bacteraemia. International Journal of Antimicrobial Agents 40(2):108-113, 2012 (August)
      (Coauthor)

      Lee JY, Ko KS*. OprD mutations and inactivation, expression of efflux pumps and AmpC, and metallo-β-lactamases in carbapenem-resistant Pseudomonas aeruginosa isolates from South Korea. International Journal of Antimicrobial Agents 40(2):168-172, 2012 (August)
      (Corresponding author)

      Shin J, Choi MJ, Ko KS*. Replicon sequence typing of IncF plasmids and the genetic environments of blaCTX-M-15 indicate multiple acquisitions of blaCTX-M-15 in Escherichia coli and Klebsiella pneumoniae isolates from South Korea. Journal of Antimicrobial Chemotherapy 67(8):1853-1857, 2012 (August)
      (Corresponding author)

      Sa HS, Ko KS*, Woo KI, Peck KR, Kim YD. A case of sino-orbital infection caused by the Schizophyllum commune. Diagnostic Microbiology and Infectious Disease 73(4):376-377, 2012 (August)
      (Co-first author)

      Joo EJ, Chung DR, Ha YE, Park SY, Kang SJ, Kim SH, Kang CI, Peck KR, Lee NY, Ko KS, Song JH. Community associated PVL-negative MRSA clone (ST72-MRSA-IV) causing healthcare-associated pneumonia and surgical site infection in Korea. Journal of Hospital Infection 81(3):149-155, 2012 (July)
      (Coauthor)

      Joo EJ, Chung DR, Ha YE, Park SY, Kim HA, Lim MH, Kim SH, Kang CI, Lee NY, Ko KS, Peck KR, Song JH. Clinical predictors of community-genotype ST72-methcillin-resistant Staphylococcus aureus SCCmec type IV in patients with community-onset S. aureus infection. Journal of Antimicrobial Chemotherapy 67(7):1755-1759, 2012 (July)
      (Coauthor)

      Kim DH, Park YK, Choi JY, Ko KS*. Identification of genetic recombination between Acinetobacter species based on multilocus sequence analysis. Diagnostic Microbiology and Infectious Disease 73(3):283-286, 2012 (July)
      (Corresponding author)

      Chung DR, Park MH, Kim SH, Ko KS, Kang CI, Peck KR, Song JH. Prevalence and molecular characterization of serotype K1 Klebsiella pneumoniae strains from various clinical specimen sources in 11 Asian countries. Journal of Infection 64(6):622-625, 2012 (June)
      (Coauthor)

      Seo JY, Yeom JS, Ko KS*. Actinomyces cardiffensis septicemia: A case report. Diagnostic Microbiology and Infectious Disease 73:198-200, 2012 (May)
      (Corresponding author)

      Cheong HS, Ko KS, Kang CI, Chung DR, Peck KR, Song JH. Clinical significance of infections caused by extended-spectrum β-lactamase-producing Enterobacteriaceae blood isolates with inducible AmpC β-lactamase. Microbial Drug Resistance 18(4):446-452, 2012 (August)
      (Coauthor)

      Kang CI, Chung DR, Ko KS, Peck KR, Song JH. The Korean Network for Study of Infectious Diseases (KONSID). Risk factors for infection and treatment outcome of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae bacteremia in patients with hematologic malignancy. Annals of Hematology 91(1):115-121, 2012 (January)
      (Coauthor)

      Chung DR, Lee H, Park MH, Jung SI, Chang HH, Kim YS, Son JS, Moon C, Kwon KT, Ryu SY, Shin SY, Ko KS, Kang CI, Peck KR, Song JH. Fecal carriage of serotype K1 Klebsiella pneumoniae ST23 strains closely related to liver abscess isolates in Koreans living in Korea. European Journal of Clinical Microbiology and Infectious Disease 31(4): 481-486, 2012 (April)
      (Co-author)

      Lee JY, Ko KS*. Antimicrobial resistance and clones of Acinetobacter species and Pseudomonas aeruginosa. Journal of Bacteriology and Virology 42(1):1-8, 2012 (March)
      (Corresponding author)

      Kang CI, Song JH, Ko KS, Chung DR, Peck KR Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study Group. Clinical features and outcomes of Staphylococcus aureus infections in non-neutropenic cancer patients. Supportive Care in Cancer 20(3):483-488, 2012 (March)
      (Coauthor)

      Sohn KM, Chung DR, Baek JY, Kim SH, Joo EJ, Ha YE, Ko KS, Kang CI, Peck KR, Song JH. Post-influenza pneumonia caused by the USA300 community-associated methicillin-resistant Staphylococcus aureus in Korea. Journal of Korean Medical Science 27(3):313-316, 2012 (March)
      (Coauthor)

      Ko KS*, Baek JY, Song JH. Multidrug-resistant Streptococcus pneumoniae serotype 6D clones in South Korea. Journal of Clinical Microbiology 50(3):818-822, 2012 (March)
      (First & co-corresponding author)

      Peck KR, Kim MJ, Choi JY, Kim HS, Kang CI, Cho YK, Park DW, Lee HJ, Lee MS, Ko KS*. In vitro time-kill studies of antimicrobial agents against blood isolates of imipenem-resistant Acinetobacter baumannii including colistin- or tigecycline-resistant isolates. Journal of Medical Microbiology 61(3):353-360, 2012 (March)
      (Corresponding author)

      Kim SH, Song JH, Chung DR, Thamlikitkul V, Yang Y, Wang H, Lu M, So T, Hsueh PR, Yasin R, Carlos C, Pham HV, Lalitha MK, Shimono N, Perera J, Shibl A, Baek JY, Kang CI, Ko KS, Peck KR on behalf of the ANSORP Study Group. Changing trend of antimicrobial resistance and serotypes in Streptococcus pneumoniae in Asian countries: an ANSORP study. Antimicrobial Agents and Chemotherapy 56(3):1418-1426, 2012 (March)
      (Co-author)

      Lee JY, Lim MH, Heo ST, Ko KS*. Repeated isolation of Pseudomonas aeruginosa isolates resistant to both polymyxins and carbapenems from one patient. Diagnostic Microbiology and Infectious Disease 72(3):267-271, 2012 (March)
      (Corresponding author)

      Kang CI, Wi YM, Lee MY, Ko KS, Chung DR, Peck KR, Lee NY, Song JH. Epidemiology and risk factors of community-onset infections caused by extended-spectrum β-lactamase-producing Escherichia coli. Journal of Clinical Microbiology 50(2): 312-317, 2012 (February)
      (Coauthor)

      Park YK, Jung SI, Park KH, Kim DH, Choi JY, Kim SH, Ko KS*.Changes in antimicrobial susceptibility and major clones of Acinetobacter calcoaceticus-baumannii isolates from a single hospital in Korea over 7 years. Journal of Medical Microbiology 61(1):71-79, 2012 (January)
      (Corresponding author)

      Park YK, Jung SI, Park KH, Kim SH, Ko KS*. Characteristics of carbapenem-resistant Acinetobacter species other than A. baumannii in Korea. International Journal of Antimicrobial Agents 39(1):81-85, 2012 (January).
      (Corresponding author)

      Kang CI, Chung DR, Ko KS, Peck KR, Song JH Korean Network for Study of Infectious Diseases (KONSID). Clinical predictors of Enterobacter bacteremia among patients admitted to the ED. American Journal of Emergency Medicine 30(1):165-169, 2012 (January)
      (Coauthor)


      [2011]
      Chung DR, Song JH, Kim SH, Thamlikitkul V, Huang SG, Wang H, So TM, Yasin RM, Hsueh PR, Carlos CC, Hsu LY, Buntaran L, Lalitha MK, Kim MJ, Choi JY, Kim SI, Ko KS, Kang CI, Peck KR on behalf of the ANSORP Study Group. High Prevalence of Multidrug-Resistant Non-Fermenters in Hospital-Acquired Pneumonia in Asia. American Journal of Respiratory and Critical Care Medicine 184:1409-1417, 2011 (December)
      (Coauthor)

      Heo ST, Oh WS, Kim SJ, Bae IG, Ko KS*, Lee JC. Clinical impacts of a single clone (ST92) of multidrug resistant Acinetobacter baumannii in intensive care units. Microbial Drug Resistance 17(4):559-562, 2011 (December)
      (Co-Corresponding author)

      Baek JY, Ko KS*, Kang CI, Song JH, Peck KR. In vitro antibacterial activities of doripenem, imipenem, and meropenem against recent Streptococcus pneumoniae isolates. Diagnostic Microbiology and Infectious Disease 71(3):297-300, 2011 (November)
      (Co-Corresponding author)

      Lee MY, Ko KS*, Kang CI, Chung DR, Peck KR, Song JH. High prevalence of CTX-M-15-producing Klebsiella pneumoniae isolates in Asian countries: diverse clones and clonal dissemination. International Journal of Antimicrobial Agents 38(2):160-163, 2011 (August)
      (Corresponding author)

      Shin J, Kim DH, Ko KS*. Comparison of CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae isolates from patients with bacteremia. Journal of Infection 63(1):39-47, 2011 (July)
      (Corresponding author)

      Lee J, Kang CI, Joo EJ, Ha YE, Park SY, Chung DR, Peck KR, Ko KS, Lee NY, Song JH. Epidemiology and clinical features of community-onset bacteremia caused by extended-spectrum β-lactamase–producing Klebsiella pneumoniae. Microbial Drug Resistance 17(2):267-273, 2011 (June)
      (Coauthor)

      Park YK, Choi JY, Shin D, Ko KS*. Correlation between overexpression and amino acid substitution of PmrAB locus and colistin resistance in Acinetobacter baumannii. International Journal of Antimicrobial Agents 37(6):525-530, 2011 (June)
      (Corresponding author)

      Lee JY, Song JH, Ko KS*. Identification of nonclonal Pseudomonas aeruginosa with reduced colistin susceptibility in Korea. Microbial Drug Resistance 17(2):299-304, 2011 (June)
      (Corresponding author)

      Song JH, Baek JY, Ko KS*. Comparison of capsular genes of Streptococcus pneumoniae serotype 6A, 6B, 6C, and 6D isolates. Journal of Clinical Microbiology 49(5):1758-1764, 2011 (May)
      (Corresponding author)

      Kim DS, Wi YM, Choi JY, Peck KR, Song JH, Ko KS*. Bacteremia caused by Laribacter hongkongensis misidentified as Acinetobacter lwoffii: report of first case in Korea. Journal of Korean Medical Science 26(5):679-681, 2011 (May)
      (Corresponding author)

      Song JH, Hsueh PR, Chung DR, Ko KS, Kang CI, Peck KR, Yeom JS, Kim SW, Chang HH, Kim YS, Jung SI, Son JS, So TM, Lalitha MK, Yang Y, Huang SG, Wang H, Lu Q, Carlos CC, Perera JA, Chiu CH, Liu JW, Chongthaleong A, Thamlikikul V, Van PH, on behalf of the ANSORP Study Group. Spread of methicillin-resistant Staphylococcus aureus between the community and the hospitals in Asian countries: an ANSORP study. Journal of Antimicrobial Chemotherapy 66(5):1061-1069, 2011 (May)
      (Coauthor)

      Shin J, Baek JY, Kim SH, Song JH, Ko KS*. Predominance of ST320 among Streptococcus pneumoniae serotype 19A isolates from 10 Asian countries. Journal of Antimicrobial Chemotherapy 66(5):1001-1004, 2011 (May)
      (Corresponding author)

      Ko KS*, Lim SK, Jung SC, Yoon JM, Choi JY, Song JH. Sequence type 72 methicillin-resistant Staphylococus aureus isolates from humans, raw meat, and soil in South Korea. Journal of Medical Microbiology 60(4):442-445, 2011 (April).
      (The first and corresponding author)

      Baek JY, Ko KS*, Kim SH, Kang CI, Chung DR, Peck KR, Song JH. Comparison of methods for detection of Streptococcus pneumoniae serotype 6C. Diagnostic Microbiology and Infectious Disease 69(4):457-459, 2011 (April)
      (Corresponding author)

      Baek JY, Ko KS*, Kim SH, Kang CI, Chung DR, Peck KR, Song JH. Comparison of genotypes of Streptococcus pneumoniae serotypes 6A and 6B before and after the introduction of PCV7 vaccination in Korea. Diagnostic Microbiology and Infectious Disease 69(4):370-375, 2011 (April)
      (Corresponding author)

      Lee H, Ko KS*, Song JH, Peck KR. Antimicrobial activity of doripenem and other carbapenems against Gram-negative pathogens from Korea. Microbial Drug Resistance 17(1):37-45, 2011 (March)
      (Corresponding author)

      Kang CI, Chung DR, Son JS, Ko KS, Peck KR, Song JH, KONSID. Clinical significance of nosocomial acquisition in urinary tract-related bacteremia caused by gram-negative bacilli. American Journal of Infection Control 39(2):135-140, 2011 (March)
      (Coauthor)

      Kang CI, Chung DR, Ko KS, Peck KR, Song JH. Risk factors for mortality and impact of broad-spectrum cephalosporin resistance on outcome in bacteraemic intra-abdominal infections caused by Gram-negative bacilli. Scandinavian Journal of Infectious Diseases 43(3):202-208, 2011 (March)
      (Coauthor)

      Yang HJ, Yim HW, Lee MY, Ko KS*, Yoon HJ. Mycobacterium conceptionense infection complicating face rejuvenation with fat grafting. Journal of Medical Microbiology 60(3):371-374, 2011 (March)
      (Corresponding author)

      Baek JY, Ko KS*, Song JH. Streptococcus pneumoniae serotype 6D cross-reacting with serotypes 6A, 6B, and 6C factor sera. Journal of Clinical Mirobiology 49(2):465-466, 2011. (February)
      (Corresponding author)

      Kim SY, Ko KS*, Moon SY, Lee MS, Lee MY, Song JS. Catheter-related candidemia caused by Candida haemulonii in a patient in long-term hospital care. Journal of Korean Medical Science 26(2):297-300, 2011. (February)
      (Co-first author)

      Croucher NJ, Harris SR, Fraser C, Quail MA, Burton J, van der Linden M, McGee L, von Gottberg A, Song JH, Ko KS, Pichon B, Baker S, Parry CM, Lambersten LM, Shahinas D, Pillai DR, Mitchell TJ, Dougan G, Tomasz A, Klugman KP, Parkhill J, Hanage WP, Bentley SD. Rapid pneumococcal evolution in response to clinical interventions. Science 331: 430-434. 2011 (January 28)
      (Coauthor)

      Kang CI, Song JH, Chung DR, Peck KR, Ko KS, Yeom JS, Ki HK, Son JS, Lee SS, Kim YS, Jung SI, Kim SW, Chang HH, Ryu SY, Kwon KT, Lee H, Moon C on behalf of Korean Network for Study of Infectious Diseases (KONSID). Risk factors and pathogenic significance of severe sepsis and septic shock in 2,286 patients with gram-negative bacteremia. Journal of Infection 62(1):26-33, 2011 (January).
      (Coauthor)

      Kang CI, Song JH, Ko KS, Chung DR, Peck KR the Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study Group. Clinical features and outcome of Staphylococcus aureus infection in elderly and younger adult patients. International Journal of Infectious Diseases 15(1):e58-e62, 2011 (January)
      (Coauthor)

      Choi HJ, Nam D, Peck KR, Song JH, Shin D, Ko KS*. Loss of vancomycin resistance not completely dependent on the Tn1546 element in Enterococcus faecium isolates. Diagnostic Microbiology and Infectious Disease 69(1):105-110, 2011 (January)
      (Corresponding author)

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