SUNGKYUNKWAN UNIVERSITY SCHOOL OF MEDICINE
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Jaejun Kim
Jaejun Kim PhD
| Graduate Program | Development and Regenerative Medicine |
| Research Area | Gene Therapy, Cell Therapy, Liver regeneration |
| Laboratory | Gene Medicine Lab Laboratory |
| jaejun.kim@skku.edu | |
| Tel | 031-299-6128 |
Education & Careers
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Assistant Professor, School of Medicine, Sungkyunkwan University (2025 - present)
Postdoctoral fellow, Department of Regeneration Medicine, University of California San Francisco (2019 - 2025)
Postdoctoral fellow, College of Veterinary Medicine, Seoul National University (2018 - 2019)
Ph.D., College of Medicine, Seoul National University (2012 - 2018)
B.S. & D.V.M., College of Veterinary Medicine, Seoul National University (2006 - 2012)
Research Interest
Our lab is dedicated to developing innovative gene therapies for currently incurable diseases. We design Adeno-Associated Virus (AAV) vectors that deliver genes more efficiently and precisely to target tissues, and we build advanced mouse models that more faithfully recapitulate human biology. In parallel, we are pioneering gene therapy strategies to repair the liver, with the ultimate goal of creating transformative treatments.
Major Areas of Research
1. Development of novel AAV capsids with improved tissue targeting
2. Generation of humanized mouse models for AAV capsid screening
3. Mechanisms and therapeutic strategies for treating liver diseases
Major Areas of Research
1. Development of novel AAV capsids with improved tissue targeting
2. Generation of humanized mouse models for AAV capsid screening
3. Mechanisms and therapeutic strategies for treating liver diseases
Representative Research Achievements
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Kim J-J*, Kurial S*, Choksi P, Nunez M, Lunow-Luke T, Bartel J, Driscoll J, Her C, Dhillon S, Yue W, Murti A, Mao T, Ramos J, Tiyaboonchai A, Grompe M, Mattis A, Syed S, Wang B, Maher J, Roll G, Willenbring H. AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion. Nature Biotechnology. 2025 Jan. (*co-first authors)
Kim J-J*, Kim D-H*, Lee JY, Kang I, Lee B-C, Koog MG, Choi SW, Woo H-M, Kang K-S. cAMP/EPAC signaling enables ETV2 to induce endothelial cells with high angiogenesis potential. Molecular Therapy. 2020 Feb. (*co-first authors)
Yu K-R*, Shin J-H*, Kim J-J*, Koog MG, Lee JY, Choi SW, Kim H-S, Seo Y, Lee S, Shin T-h, Jee MK, Kim D-W, Jun SJ, Shin S, Han DW, Kang K-S. Rapid and efficient direct conversion of human adult somatic cells into neural stem cells by HMGA2/let-7b. Cell Reports. 2015 Jan. (*co-first authors)
Choi SW*, Kim J-J*, Seo M-S, Park S-B, Kang T-W, Lee JY, Lee B-C, Kang I, Shin T-H, Kim H-S, Yu K-R, Kang K-S. miR-410 inhibition induces RPE differentiation of amniotic epithelial stem cells via overexpression of OTX2 and RPE65. Stem Cell Reviews and Reports. 2015 Jun. (*co-first authors)