SUNGKYUNKWAN UNIVERSITY SCHOOL OF MEDICINE
CLOSE HEADER
Laboratory
Cancer Metastasis & Stem Cell Laboratory(암전이줄기세포연구실)
Kyeung Min Joo
Cancer Biology, Neuroscience, Biomedical Therapeutics Laboratory
Mesenchymal stem cell therapies have been studied in some diseases which are cancer, neurological pathologies, musculoskeletal disorders etc. as alternative option. In previous studies, MSCs were improved that they have therapeutic effect to treat various diseases. However, to approach clinical trials, it needs evidence that shows MSCs haven’t serious side effect during their migration or drug delivery times. In present, we are focused on stem cell engineering by immortalization and enucleation to minimize side effects and maximize therapeutic effects for therapy NSCLCs to brain metastatic tumor, Ischemic Stroke and Multiple Sclerosis.
- Google Scholar: https://scholar.google.com/citations?user=wFzz-lEAAAAJ&hl=en
- Research Gate: https://www.researchgate.net/profile/Kyeung_Min_Joo
1. Ha, G. H., Yeon, J. Y., Kim, K. H., Lee, D. M., Chae, H. Y., Nam, H., ... & Joo, K. M. (2024). Thrombin Priming Promotes the Neuroprotective Effects of Human Whartons Jelly-Derived Mesenchymal Stem Cells Via the HGF/AKT/STAT3 Signaling Pathway. Stem Cells and Development, 33(3-4), 89-103.
2. Nam, H., Lee, I. H., Sa, J. K., Kim, S. S., Pyeon, H. J., Lee, K. H., ... & Joo, K. M. (2022). Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells. Stem Cell Reviews and Reports, 1-17.
3. Kim, S. S., Pyeon, H. J., Bae, Y. K., Nam, H., Kim, C. K., Lee, S. H., & Joo, K. M. (2021). Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP&82081 and GRO. Stem Cells International, 2021(1), 6737288.
4. Kim, S. S. Pyeon, H. J. Bae, Y. K. Nam, H. Kim, C. K. Lee, S. H. Joo, K. M., Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP-1 and GRO. Stem Cells Int 2021, 2021, 6737288.
5. Bae YK, Kim GH, Lee JC, Seo BM, Joo KM, Lee G, Nam H, 2017: The Significance of SDF-1α-CXCR4 Axis in in vivo Angiogenic Ability of Human Periodontal Ligament Stem Cells.. Mol Cells, 40(6), 386-392
6. Lee KH, Nam H, Jeong da E, Kim SS, Song HJ, Pyeon HJ, Kang K, Hong SC, Nam DH, Joo KM., 2016: Sensitive Tumorigenic Potential Evaluation of Adult Human Multipotent Neural Cells Immortalized by hTERT Gene Transduction.. PLoS One, 11(7), e0158639
- Research Gate: https://www.researchgate.net/profile/Kyeung_Min_Joo
1. Ha, G. H., Yeon, J. Y., Kim, K. H., Lee, D. M., Chae, H. Y., Nam, H., ... & Joo, K. M. (2024). Thrombin Priming Promotes the Neuroprotective Effects of Human Whartons Jelly-Derived Mesenchymal Stem Cells Via the HGF/AKT/STAT3 Signaling Pathway. Stem Cells and Development, 33(3-4), 89-103.
2. Nam, H., Lee, I. H., Sa, J. K., Kim, S. S., Pyeon, H. J., Lee, K. H., ... & Joo, K. M. (2022). Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells. Stem Cell Reviews and Reports, 1-17.
3. Kim, S. S., Pyeon, H. J., Bae, Y. K., Nam, H., Kim, C. K., Lee, S. H., & Joo, K. M. (2021). Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP&82081 and GRO. Stem Cells International, 2021(1), 6737288.
4. Kim, S. S. Pyeon, H. J. Bae, Y. K. Nam, H. Kim, C. K. Lee, S. H. Joo, K. M., Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP-1 and GRO. Stem Cells Int 2021, 2021, 6737288.
5. Bae YK, Kim GH, Lee JC, Seo BM, Joo KM, Lee G, Nam H, 2017: The Significance of SDF-1α-CXCR4 Axis in in vivo Angiogenic Ability of Human Periodontal Ligament Stem Cells.. Mol Cells, 40(6), 386-392
6. Lee KH, Nam H, Jeong da E, Kim SS, Song HJ, Pyeon HJ, Kang K, Hong SC, Nam DH, Joo KM., 2016: Sensitive Tumorigenic Potential Evaluation of Adult Human Multipotent Neural Cells Immortalized by hTERT Gene Transduction.. PLoS One, 11(7), e0158639
(Tel) +82-31-299-6073,
(Email) kmjoo@skku.edu